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Kidney Organoids as a Novel Platform to Evaluate Lipopolysaccharide-Induced Oxidative Stress and Apoptosis in Acute Kidney Injury

Sepsis-associated acute kidney injury (SA-AKI) is a life-threatening syndrome. Lipopolysaccharide (LPS) is a widely used inducer for modeling SA-AKI both in vivo and in vitro. However, due to the innate complexity of the kidney architecture, the mechanisms underlying the pathogenesis of SA-AKI, as w...

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Detalles Bibliográficos
Autores principales: Zhang, Weitao, Qi, Ruochen, Li, Tingting, Zhang, Xuepeng, Shi, Yi, Xu, Ming, Zhu, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666666/
https://www.ncbi.nlm.nih.gov/pubmed/34912825
http://dx.doi.org/10.3389/fmed.2021.766073