TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance

Few studies have explored the association between SNPs and alterations in mRNA translation potential. We developed an approach to identify SNPs that can mark allele-specific protein expression levels and could represent sources of inter-individual variation in disease risk. Using MCF7 cells under di...

Descripción completa

Detalles Bibliográficos
Autores principales: Valentini, Samuel, Marchioretti, Caterina, Bisio, Alessandra, Rossi, Annalisa, Zaccara, Sara, Romanel, Alessandro, Inga, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666669/
https://www.ncbi.nlm.nih.gov/pubmed/34917903
http://dx.doi.org/10.1016/j.isci.2021.103531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666669/
https://www.ncbi.nlm.nih.gov/pubmed/34917903
http://dx.doi.org/10.1016/j.isci.2021.103531

Ejemplares similares