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TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance
Few studies have explored the association between SNPs and alterations in mRNA translation potential. We developed an approach to identify SNPs that can mark allele-specific protein expression levels and could represent sources of inter-individual variation in disease risk. Using MCF7 cells under di...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666669/ https://www.ncbi.nlm.nih.gov/pubmed/34917903 http://dx.doi.org/10.1016/j.isci.2021.103531 |