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Fine-tuning spermidine binding modes in the putrescine binding protein PotF

A profound understanding of the molecular interactions between receptors and ligands is important throughout diverse research, such as protein design, drug discovery, or neuroscience. What determines specificity and how do proteins discriminate against similar ligands? In this study, we analyzed fac...

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Detalles Bibliográficos
Autores principales: Kröger, Pascal, Shanmugaratnam, Sooruban, Scheib, Ulrike, Höcker, Birte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666671/
https://www.ncbi.nlm.nih.gov/pubmed/34801550
http://dx.doi.org/10.1016/j.jbc.2021.101419