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Amodiaquine promotes testosterone production and de novo synthesis of cholesterol and triglycerides in Leydig cells

Testosterone is a hormone essential for male reproductive function. It is produced primarily by Leydig cells in the testicle through activation of steroidogenic acute regulatory protein and a series of steroidogenic enzymes, including a cytochrome P450 side-chain cleavage enzyme (cytochome P450 fami...

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Detalles Bibliográficos
Autores principales: Choi, Yujeong, Lee, Eun Goo, Lee, Gibbeum, Jeong, Mi Gyeong, Kim, Hyo Kyeong, Oh, Ji-Hyun, Kwon, Sung Won, Hwang, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666709/
https://www.ncbi.nlm.nih.gov/pubmed/34808194
http://dx.doi.org/10.1016/j.jlr.2021.100152