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NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy
Pregnancy is a common immunization event, but the molecular mechanisms and immunological consequences provoked by pregnancy remain largely unknown. We used mouse models and human transplant registry data to reveal that pregnancy induced exhausted CD8 T cells (Preg-T(EX)), which associated with prolo...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666877/ https://www.ncbi.nlm.nih.gov/pubmed/34882194 http://dx.doi.org/10.1084/jem.20201599 |