CNS GNPDA2 Does Not Control Appetite, but Regulates Glucose Homeostasis

GNPDA2 has been associated with human obesity and type-2 diabetes by using a GWAS approach. GNPDA2 is an enzyme involved in the hexosamine biosynthesis pathway, which is known to be important for nutrient sensing in various organism. Its counter enzyme, GFAT, has previously been shown to be importan...

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Detalles Bibliográficos
Autores principales: Gutierrez-Aguilar, Ruth, Grayson, Bernadette E., Kim, Dong-Hoon, Yalamanchili, Suma, Calcagno, Mario L., Woods, Stephen C., Seeley, Randy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666973/
https://www.ncbi.nlm.nih.gov/pubmed/34912841
http://dx.doi.org/10.3389/fnut.2021.787470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666973/
https://www.ncbi.nlm.nih.gov/pubmed/34912841
http://dx.doi.org/10.3389/fnut.2021.787470

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