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CNS GNPDA2 Does Not Control Appetite, but Regulates Glucose Homeostasis
GNPDA2 has been associated with human obesity and type-2 diabetes by using a GWAS approach. GNPDA2 is an enzyme involved in the hexosamine biosynthesis pathway, which is known to be important for nutrient sensing in various organism. Its counter enzyme, GFAT, has previously been shown to be importan...
Autores principales: | Gutierrez-Aguilar, Ruth, Grayson, Bernadette E., Kim, Dong-Hoon, Yalamanchili, Suma, Calcagno, Mario L., Woods, Stephen C., Seeley, Randy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666973/ https://www.ncbi.nlm.nih.gov/pubmed/34912841 http://dx.doi.org/10.3389/fnut.2021.787470 |
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