Clinicopathologic Implications of Complement Genetic Variants in Kidney Transplantation

Genetic testing has uncovered rare variants in complement proteins associated with thrombotic microangiopathy (TMA) and C3 glomerulopathy (C3G). Approximately 50% are classified as variants of uncertain significance (VUS). Clinical risk assessment of patients carrying a VUS remains challenging prima...

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Detalles Bibliográficos
Autores principales: Ren, Zhen, Perkins, Stephen J., Love-Gregory, Latisha, Atkinson, John P., Java, Anuja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666976/
https://www.ncbi.nlm.nih.gov/pubmed/34912830
http://dx.doi.org/10.3389/fmed.2021.775280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666976/
https://www.ncbi.nlm.nih.gov/pubmed/34912830
http://dx.doi.org/10.3389/fmed.2021.775280

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