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Clinicopathologic Implications of Complement Genetic Variants in Kidney Transplantation

Genetic testing has uncovered rare variants in complement proteins associated with thrombotic microangiopathy (TMA) and C3 glomerulopathy (C3G). Approximately 50% are classified as variants of uncertain significance (VUS). Clinical risk assessment of patients carrying a VUS remains challenging prima...

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Detalles Bibliográficos
Autores principales:	Ren, Zhen, Perkins, Stephen J., Love-Gregory, Latisha, Atkinson, John P., Java, Anuja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666976/ https://www.ncbi.nlm.nih.gov/pubmed/34912830 http://dx.doi.org/10.3389/fmed.2021.775280

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