Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

The ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain (CARD)) protein is an scaffold component of different inflammasomes, intracellular multiprotein platforms of the innate immune system that are activated in response to pathogens or intracellular damage. The form...

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Detalles Bibliográficos
Autores principales: Soriano-Teruel, Paula M., García‑Laínez, Guillermo, Marco-Salvador, María, Pardo, Julián, Arias, Maykel, DeFord, Christian, Merfort, Irmgard, Vicent, María J., Pelegrín, Pablo, Sancho, Mónica, Orzáez, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667020/
https://www.ncbi.nlm.nih.gov/pubmed/34903717
http://dx.doi.org/10.1038/s41419-021-04420-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667020/
https://www.ncbi.nlm.nih.gov/pubmed/34903717
http://dx.doi.org/10.1038/s41419-021-04420-1

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