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CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles

Extracellular vesicles (EVs) transfer functional molecules between cells. CD63 is a widely recognized EV marker that contributes to EV secretion from cells. However, the regulation of its expression remains largely unknown. Ferritin is a cellular iron storage protein that can also be secreted by the...

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Detalles Bibliográficos
Autores principales: Yanatori, Izumi, Richardson, Des R., Dhekne, Herschel S., Toyokuni, Shinya, Kishi, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667049/
https://www.ncbi.nlm.nih.gov/pubmed/34265052
http://dx.doi.org/10.1182/blood.2021010995