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Propranolol inhibits stemness of hemangioma through Jagged1

BACKGROUND: Propranolol is used clinically to treat infantile hemangioma (IH), although the exact mechanism that underlies its effectiveness is not fully understood. The Jagged1/Notch signaling pathway is downstream of the β2-adrenergic receptor (β2-AR). Propranolol is a non-selective β2-AR blocker...

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Detalles Bibliográficos
Autores principales: Ma, Xiaorong, Lv, Kaiyang, Wu, Liming, Ouyang, Tianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667105/
https://www.ncbi.nlm.nih.gov/pubmed/34988191
http://dx.doi.org/10.21037/atm-21-5563