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Salidroside inhibits NLRP3 inflammasome activation and apoptosis in microglia induced by cerebral ischemia/reperfusion injury by inhibiting the TLR4/NF-κB signaling pathway

BACKGROUND: The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an important mediator of neuroinflammatory responses that regulates inflammatory injury following cerebral ischemia and may be a potential target. Salidroside (Sal) has good anti-inflammatory effects; however,...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Ma, Wei, Zang, Cheng-Hao, Wang, Guo-Dong, Zhang, Si-Jia, Wu, Hong-Jie, Zhu, Ke-Wei, Xiang, Xiang-Lin, Li, Chun-Yan, Liu, Kuang-Pin, Guo, Jian-Hui, Li, Li-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667139/
https://www.ncbi.nlm.nih.gov/pubmed/34988203
http://dx.doi.org/10.21037/atm-21-5752