Exchange proteins directly activated by cyclic adenosine monophosphate inhibitor reverses mechanical allodynia via the modification of astrocytes activity in the spinal cord

BACKGROUND: Gliosis and inflammation are pivotal in the development of acute and chronic pain. Here, we demonstrated a previously unidentified molecular mechanism in which the activation of exchange proteins directly activated by cyclic adenosine monophosphate (Epac)1 accelerated the activation of a...

Descripción completa

Detalles Bibliográficos
Autores principales: She, Qing, Chen, Junjie, Zhong, Chaochao, Huang, Saisai, Lu, Cui’e, Qin, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667141/
https://www.ncbi.nlm.nih.gov/pubmed/34988165
http://dx.doi.org/10.21037/atm-21-5384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667141/
https://www.ncbi.nlm.nih.gov/pubmed/34988165
http://dx.doi.org/10.21037/atm-21-5384

Ejemplares similares