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Exchange proteins directly activated by cyclic adenosine monophosphate inhibitor reverses mechanical allodynia via the modification of astrocytes activity in the spinal cord

BACKGROUND: Gliosis and inflammation are pivotal in the development of acute and chronic pain. Here, we demonstrated a previously unidentified molecular mechanism in which the activation of exchange proteins directly activated by cyclic adenosine monophosphate (Epac)1 accelerated the activation of a...

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Detalles Bibliográficos
Autores principales:	She, Qing, Chen, Junjie, Zhong, Chaochao, Huang, Saisai, Lu, Cui’e, Qin, Yibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667141/ https://www.ncbi.nlm.nih.gov/pubmed/34988165 http://dx.doi.org/10.21037/atm-21-5384

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