Cargando…

PDGF Promotes Dermal Fibroblast Activation via a Novel Mechanism Mediated by Signaling Through MCHR1

Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy and excessive fibrosis of the skin and internal organs. To this day, no effective treatments to prevent the progression of fibrosis exist, and SSc patients have disabilities and reduced life expectancy. The need to bette...

Descripción completa

Detalles Bibliográficos
Autores principales: Takamura, Naoko, Renaud, Ludivine, da Silveira, Willian Abraham, Feghali-Bostwick, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667318/
https://www.ncbi.nlm.nih.gov/pubmed/34912333
http://dx.doi.org/10.3389/fimmu.2021.745308