Cargando…

Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4(+)CD25(+) Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor

CD4(+)CD25(+)Foxp3(+)T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cytokines. Third, effector lineage CD4(+)CD25(+)T...

Descripción completa

Detalles Bibliográficos
Autores principales: Hall, Bruce M., Hall, Rachael M., Tran, Giang T., Robinson, Catherine M., Wilcox, Paul L., Rakesh, Prateek K., Wang, Chuanmin, Sharland, Alexandra F., Verma, Nirupama D., Hodgkinson, Suzanne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667344/
https://www.ncbi.nlm.nih.gov/pubmed/34912327
http://dx.doi.org/10.3389/fimmu.2021.714838