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A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics

BACKGROUND: Recent genome-wide association studies (GWASs) have revealed the polygenic nature of psychiatric disorders and discovered a few of single-nucleotide polymorphisms (SNPs) associated with multiple psychiatric disorders. However, the extent and pattern of pleiotropy among distinct psychiatr...

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Detalles Bibliográficos
Autores principales: Lu, Haojie, Qiao, Jiahao, Shao, Zhonghe, Wang, Ting, Huang, Shuiping, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667366/
https://www.ncbi.nlm.nih.gov/pubmed/34895209
http://dx.doi.org/10.1186/s12916-021-02186-z