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SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties

SARS-CoV-2 infection produces neuroinflammation as well as neurological, cognitive (i.e., brain fog), and neuropsychiatric symptoms (e.g., depression, anxiety), which can persist for an extended period (6 months) after resolution of the infection. The neuroimmune mechanism(s) that produces SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Frank, Matthew G., Nguyen, Kathy H., Ball, Jayson B., Hopkins, Shelby, Kelley, Tel, Baratta, Michael V., Fleshner, Monika, Maier, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667429/
https://www.ncbi.nlm.nih.gov/pubmed/34915155
http://dx.doi.org/10.1016/j.bbi.2021.12.007