Chemokine (C-C Motif) Ligand 2/Chemokine Receptor 2 (CCR2) Axis Blockade to Delay Chondrocyte Hypertrophy as a Therapeutic Strategy for Osteoarthritis

BACKGROUND: Chondrocytes play a vital role in the later stages of osteoarthritis (OA). The roles of chemokine (C-C motif) ligand 2 (CCL2) and its receptor, chemokine receptor 2 (CCR2), are as yet poorly elucidated in chondrocyte hypertrophy (CH). Here, we aimed to regulate the CCL2/CCR2 axis and exp...

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Detalles Bibliográficos
Autores principales: Wang, Zidong, Wang, Bei, Zhang, Jian, Wu, Zhensong, Yu, Liankui, Sun, Zhongye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667482/
https://www.ncbi.nlm.nih.gov/pubmed/34876548
http://dx.doi.org/10.12659/MSM.930053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667482/
https://www.ncbi.nlm.nih.gov/pubmed/34876548
http://dx.doi.org/10.12659/MSM.930053

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