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Quantifying the regulatory role of individual transcription factors in Escherichia coli
Gene regulation often results from the action of multiple transcription factors (TFs) acting at a promoter, obscuring the individual regulatory effect of each TF on RNA polymerase (RNAP). Here we measure the fundamental regulatory interactions of TFs in E. coli by designing synthetic target genes th...
Autores principales: | Guharajan, Sunil, Chhabra, Shivani, Parisutham, Vinuselvi, Brewster, Robert C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667592/ https://www.ncbi.nlm.nih.gov/pubmed/34758318 http://dx.doi.org/10.1016/j.celrep.2021.109952 |
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