Neurogenic Hypertension Mediated Mitochondrial Abnormality Leads to Cardiomyopathy: Contribution of UPR(mt) and Norepinephrine-miR- 18a-5p-HIF-1α Axis

Aims: Hypertension increases the risk of heart disease. Hallmark features of hypertensive heart disease is sympathoexcitation and cardiac mitochondrial abnormality. However, the molecular mechanisms for specifically neurally mediated mitochondrial abnormality and subsequent cardiac dysfunction are u...

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Detalles Bibliográficos
Autores principales: Nandi, Shyam S., Katsurada, Kenichi, Mahata, Sushil K., Patel, Kaushik P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667690/
https://www.ncbi.nlm.nih.gov/pubmed/34912235
http://dx.doi.org/10.3389/fphys.2021.718982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667690/
https://www.ncbi.nlm.nih.gov/pubmed/34912235
http://dx.doi.org/10.3389/fphys.2021.718982

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