Cargando…

Overexpression of fucosyltransferase 8 reverses the inhibitory effect of high-dose dexamethasone on osteogenic response of MC3T3-E1 preosteoblasts

BACKGROUND: Core fucosylation catalyzed by FUT8 is essential for TGF-β binding to TGF-β receptors. METHODS: Indirect TGF-β1 binding assay was used to evaluate the ability of TGF-β1 to bind to TGFBRs, Alizarin red and alkaline phosphatase staining were used to detect osteogenic differentiation and mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zhiming, Lin, Tianye, Kang, Pan, Zhuang, Zhikun, Wang, Haibin, He, Wei, Wei, Qiushi, Li, Ziqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667747/
https://www.ncbi.nlm.nih.gov/pubmed/34966572
http://dx.doi.org/10.7717/peerj.12380