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TFE3-Mediated Autophagy is Involved in Dopaminergic Neurodegeneration in Parkinson’s Disease

Impairment of autophagy has been strongly implicated in the progressive loss of nigral dopaminergic neurons in Parkinson’s disease (PD). Transcription factor E3 (TFE3), an MiTF/TFE family transcription factor, has been identified as a master regulator of the genes that are associated with lysosomal...

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Detalles Bibliográficos
Autores principales: He, Xin, Xie, Yue, Zheng, Qiongping, Zhang, Zeyu, Ma, Shanshan, Li, Junyu, Li, Mingtao, Huang, Qiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667775/
https://www.ncbi.nlm.nih.gov/pubmed/34912803
http://dx.doi.org/10.3389/fcell.2021.761773