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Antiphospholipid Antibodies From Women With Pregnancy Morbidity and Vascular Thrombosis Induce Endothelial Mitochondrial Dysfunction, mTOR Activation, and Autophagy

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombosis and pregnancy morbidity (PM) obstetric events together with persistent high titers of circulating antiphospholipid antibodies (aPL). Several mechanisms that explain the development of thrombosis and PM in APS includ...

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Detalles Bibliográficos
Autores principales: Rodríguez, Carlos M., Velásquez-Berrío, Manuela, Rúa, Carolina, Viana, Marta, Abrahams, Vikki M., Cadavid, Angela P., Alvarez, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667788/
https://www.ncbi.nlm.nih.gov/pubmed/34912234
http://dx.doi.org/10.3389/fphys.2021.706743