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Simultaneous Assignment and Structure Determination of Proteins From Sparsely Labeled NMR Datasets

Sparsely labeled NMR samples provide opportunities to study larger biomolecular assemblies than is traditionally done by NMR. This requires new computational tools that can handle the sparsity and ambiguity in the NMR datasets. The MELD (modeling employing limited data) Bayesian approach was assesse...

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Detalles Bibliográficos
Autores principales: Mondal, Arup, Perez, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667806/
https://www.ncbi.nlm.nih.gov/pubmed/34912846
http://dx.doi.org/10.3389/fmolb.2021.774394