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Breakers and amplifiers in chromatin circuitry: acetylation and ubiquitination control the heterochromatin machinery
Eukaryotic genomes are segregated into active euchromatic and repressed heterochromatic compartments. Gene regulatory networks, chromosomal structures, and genome integrity rely on the timely and locus-specific establishment of active and silent states to protect the genome and provide the basis for...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667873/ https://www.ncbi.nlm.nih.gov/pubmed/34303934 http://dx.doi.org/10.1016/j.sbi.2021.06.012 |