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Antiproliferative effects of sulphonamide carbonic anhydrase inhibitors C18, SLC-0111 and acetazolamide on bladder, glioblastoma and pancreatic cancer cell lines

Carbonic anhydrase IX/XII (CA IX/XII), are cell-surface enzymes typically expressed by cancer cells as a form of adaptation to hypoxia and acidosis. It has been widely reported that these proteins play pivotal roles in cancer progression fostering cell migration, aggressiveness and resistance to fir...

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Detalles Bibliográficos
Autores principales: Mussi, Silvia, Rezzola, Sara, Chiodelli, Paola, Nocentini, Alessio, Supuran, Claudiu T., Ronca, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667884/
https://www.ncbi.nlm.nih.gov/pubmed/34894950
http://dx.doi.org/10.1080/14756366.2021.2004592