Novel 3-chloro-6-nitro-1H-indazole derivatives as promising antileishmanial candidates: synthesis, biological activity, and molecular modelling studies

An efficient pathway was disclosed for the synthesis of 3-chloro-6-nitro-1H-indazole derivatives by 1,3-dipolar cycloaddition on dipolarophile compounds 2 and 3. Faced the problem of separation of two regioisomers, a click chemistry method has allowed us to obtain regioisomers of triazole-1,4 with g...

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Detalles Bibliográficos
Autores principales: Mohamed Abdelahi, Mohamed Mokhtar, El Bakri, Youness, Lai, Chin-Hung, Subramani, Karthikeyan, Anouar, El Hassane, Ahmad, Sajjad, Benchidmi, Mohammed, Mague, Joel T., Popović-Djordjević, Jelena, Goumri-Said, Souraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667887/
https://www.ncbi.nlm.nih.gov/pubmed/34894940
http://dx.doi.org/10.1080/14756366.2021.1995380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667887/
https://www.ncbi.nlm.nih.gov/pubmed/34894940
http://dx.doi.org/10.1080/14756366.2021.1995380

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