Discovery of a novel Aurora B inhibitor GSK650394 with potent anticancer and anti-aspergillus fumigatus dual efficacies in vitro

Invasive fungal infections including Candidiasis and Aspergillosis are associated with considerable morbidity and mortality in immunocompromised individuals, such as cancer patients. Aurora B is a key mitotic kinase required for the cell division of eukaryotes from fungus to man. Here, we identified...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Yuhua, Fu, Wei, Du, Liyang, Yao, Huiqiao, Hua, Zhengkang, Li, Jinyu, Lin, Zhonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667888/
https://www.ncbi.nlm.nih.gov/pubmed/34894976
http://dx.doi.org/10.1080/14756366.2021.1975693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667888/
https://www.ncbi.nlm.nih.gov/pubmed/34894976
http://dx.doi.org/10.1080/14756366.2021.1975693

Ejemplares similares