Concatenation of molecular docking and molecular simulation of BACE-1, γ-secretase targeted ligands: in pursuit of Alzheimer’s treatment

INTRODUCTION: Alzheimer's disease (AD), the most predominant cause of dementia, has evolved tremendously with an escalating frequency, mainly affecting the elderly population. An effective means of delaying, preventing, or treating AD is yet to be achieved. The failure rate of dementia drug tri...

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Detalles Bibliográficos
Autores principales: Jabir, Nasimudeen R., Rehman, Md. Tabish, Alsolami, Khadeejah, Shakil, Shazi, Zughaibi, Torki A., Alserihi, Raed F., Khan, Mohd. Shahnawaz, AlAjmi, Mohamed F., Tabrez, Shams
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667905/
https://www.ncbi.nlm.nih.gov/pubmed/34889159
http://dx.doi.org/10.1080/07853890.2021.2009124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667905/
https://www.ncbi.nlm.nih.gov/pubmed/34889159
http://dx.doi.org/10.1080/07853890.2021.2009124

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