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M. tuberculosis CRISPR/Cas proteins are secreted virulence factors that trigger cellular immune responses

The role of prokaryotic CRISPR/Cas system proteins as a defensive shield against invasive nucleic acids has been studied extensively. Non-canonical roles in pathogenesis involving intracellular targeting of certain virulence-associated endogenous mRNA have also been reported for some Type I and Type...

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Detalles Bibliográficos
Autores principales: Jiao, Jianjian, Zheng, Nan, Wei, Wenjing, Fleming, Joy, Wang, Xingyun, Li, Zihui, Zhang, Lili, Liu, Yi, Zhang, Zongde, Shen, Adong, Chuanyou, Li, Bi, Lijun, Zhang, Hongtai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667911/
https://www.ncbi.nlm.nih.gov/pubmed/34886764
http://dx.doi.org/10.1080/21505594.2021.2007621