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M. tuberculosis CRISPR/Cas proteins are secreted virulence factors that trigger cellular immune responses
The role of prokaryotic CRISPR/Cas system proteins as a defensive shield against invasive nucleic acids has been studied extensively. Non-canonical roles in pathogenesis involving intracellular targeting of certain virulence-associated endogenous mRNA have also been reported for some Type I and Type...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667911/ https://www.ncbi.nlm.nih.gov/pubmed/34886764 http://dx.doi.org/10.1080/21505594.2021.2007621 |