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Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer

Novel halogenated phenoxychalcones 2a–f and their corresponding N-acetylpyrazolines 3a–f were synthesised and evaluated for their anticancer activities against breast cancer cell line (MCF-7) and normal breast cell line (MCF-10a), compared with staurosporine. All compounds showed moderate to good cy...

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Detalles Bibliográficos
Autores principales: Halim, Peter A., Hassan, Rasha A., Mohamed, Khaled O., Hassanin, Soha O., Khalil, Mona G., Abdou, Amr M., Osman, Eman O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667918/
https://www.ncbi.nlm.nih.gov/pubmed/34894967
http://dx.doi.org/10.1080/14756366.2021.1998023