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Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer
Novel halogenated phenoxychalcones 2a–f and their corresponding N-acetylpyrazolines 3a–f were synthesised and evaluated for their anticancer activities against breast cancer cell line (MCF-7) and normal breast cell line (MCF-10a), compared with staurosporine. All compounds showed moderate to good cy...
Autores principales: | Halim, Peter A., Hassan, Rasha A., Mohamed, Khaled O., Hassanin, Soha O., Khalil, Mona G., Abdou, Amr M., Osman, Eman O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667918/ https://www.ncbi.nlm.nih.gov/pubmed/34894967 http://dx.doi.org/10.1080/14756366.2021.1998023 |
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