Dasatinib ameliorates thioacetamide-induced liver fibrosis: modulation of miR-378 and miR-17 and their linked Wnt/β-catenin and TGF-β/smads pathways

Hepatic stellate cells activation (HSCs) plays a crucial role in the pathogenesis of liver fibrosis. Specific microRNAs have been suggested to affect the activation of HSCs via various signalling pathways including TGF-β/smads and Wnt/β-catenin pathways. Dasatinib is a multitarget inhibitor of many...

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Detalles Bibliográficos
Autores principales: Zaafan, Mai A., Abdelhamid, Amr M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667920/
https://www.ncbi.nlm.nih.gov/pubmed/34894966
http://dx.doi.org/10.1080/14756366.2021.1995379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667920/
https://www.ncbi.nlm.nih.gov/pubmed/34894966
http://dx.doi.org/10.1080/14756366.2021.1995379

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