Synthesis and biological evaluation of celastrol derivatives as potent antitumor agents with STAT3 inhibition

Using STAT3 inhibitors as a potential strategy in cancer therapy have attracted much attention. Recently, celastrol has been reported that it could directly bind to and suppress the activity of STAT3 in the cardiac dysfunction model. To explore more effective STAT3 inhibiting anti-tumour drug candid...

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Detalles Bibliográficos
Autores principales: Xu, Shaohua, Fan, Ruolan, Wang, Lu, He, Weishen, Ge, Haixia, Chen, Hailan, Xu, Wen, Zhang, Jian, Xu, Wei, Feng, Yaqian, Fan, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667935/
https://www.ncbi.nlm.nih.gov/pubmed/34894961
http://dx.doi.org/10.1080/14756366.2021.2001805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667935/
https://www.ncbi.nlm.nih.gov/pubmed/34894961
http://dx.doi.org/10.1080/14756366.2021.2001805

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