TNP and its analogs: Modulation of IP6K and CYP3A4 inhibition

Inositol hexakisphosphate kinase (IP6K) is an important mammalian enzyme involved in various biological processes such as insulin signalling and blood clotting. Recent analyses on drug metabolism and pharmacokinetic properties on TNP (N(2)-(m-trifluorobenzyl), N(6)-(p-nitrobenzyl)purine), a pan-IP6K...

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Detalles Bibliográficos
Autores principales: Lee, Seulgi, Park, Bernie Byeonghoon, Kwon, Hongmok, Kim, Vitchan, Jeon, Jang Su, Lee, Rowoon, Subedi, Milan, Lim, Taehyeong, Ha, Hyunsoo, An, Dongju, Kim, Jaehoon, Kim, Donghak, Kim, Sang Kyum, Kim, Seyun, Byun, Youngjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667942/
https://www.ncbi.nlm.nih.gov/pubmed/34894957
http://dx.doi.org/10.1080/14756366.2021.2000404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667942/
https://www.ncbi.nlm.nih.gov/pubmed/34894957
http://dx.doi.org/10.1080/14756366.2021.2000404

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