Discovery of caffeoylisocitric acid as a Keap1-dependent Nrf2 activator and its effects in mesangial cells under high glucose

Diabetic nephropathy (DN) is one of the severe microvascular complications of diabetes mellitus. Oxidative stress resulting from aberrant metabolism of glucose mediates renal inflammation and fibrosis in the progression of DN. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription fac...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Huankai, Zhang, Wenting, Yang, Feng, Ai, Fengwei, Du, Dan, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667952/
https://www.ncbi.nlm.nih.gov/pubmed/34894983
http://dx.doi.org/10.1080/14756366.2021.1998025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667952/
https://www.ncbi.nlm.nih.gov/pubmed/34894983
http://dx.doi.org/10.1080/14756366.2021.1998025

Ejemplares similares