Using recombinase‐mediated cassette exchange to engineer MIN6 insulin‐secreting cells based on a newly identified safe harbor locus

AIMS/INTRODUCTION: Recent studies have identified genomic and transcript level changes along with alterations in insulin secretion in patients with diabetes and in rodent models of diabetes. It is important to establish an efficient system for testing functional consequences of these changes. We aim...

Descripción completa

Detalles Bibliográficos
Autores principales: Furukawa, Asami, Tanaka, Aya, Yamaguchi, Suguru, Kosuda, Minami, Yamana, Midori, Nagasawa, Akiko, Kohno, Genta, Ishihara, Hisamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668067/
https://www.ncbi.nlm.nih.gov/pubmed/34382357
http://dx.doi.org/10.1111/jdi.13646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668067/
https://www.ncbi.nlm.nih.gov/pubmed/34382357
http://dx.doi.org/10.1111/jdi.13646

Ejemplares similares