Cargando…

Using recombinase‐mediated cassette exchange to engineer MIN6 insulin‐secreting cells based on a newly identified safe harbor locus

AIMS/INTRODUCTION: Recent studies have identified genomic and transcript level changes along with alterations in insulin secretion in patients with diabetes and in rodent models of diabetes. It is important to establish an efficient system for testing functional consequences of these changes. We aim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Furukawa, Asami, Tanaka, Aya, Yamaguchi, Suguru, Kosuda, Minami, Yamana, Midori, Nagasawa, Akiko, Kohno, Genta, Ishihara, Hisamitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668067/ https://www.ncbi.nlm.nih.gov/pubmed/34382357 http://dx.doi.org/10.1111/jdi.13646

Ejemplares similares

A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness
por: Tanaka, Aya, et al.
Publicado: (2023)

A rare case of fulminant type 1 diabetes mellitus accompanied by both acute pancreatitis and myocarditis - case report
por: Egashira, Fujiko, et al.
Publicado: (2020)

Fibrosis-4 Index Is Closely Associated with Arterial Damage and Future Risk of Coronary Heart Disease in Type 2 Diabetes
por: Watanabe, Kentaro, et al.
Publicado: (2022)

Recombinase‐mediated integration of a multigene cassette in rice leads to stable expression and inheritance of the stacked locus
por: Pathak, Bhuvan, et al.
Publicado: (2020)

Acute esophageal necrosis after cellulitis in an obese patient with diabetes mellitus
por: Tanaka, Sho, et al.
Publicado: (2019)

Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome
por: Wallen, Mark C., et al.
Publicado: (2015)

Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors
por: Ramachandra, Chrishan J. A., et al.
Publicado: (2011)

Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus
por: Ordovás, Laura, et al.
Publicado: (2016)

Production of viral vectors using recombinase-mediated cassette exchange
por: Nakano, Masakazu, et al.
Publicado: (2005)

Flexible pseudotyping of retrovirus using recombinase-mediated cassette exchange
por: Soares, Hugo R., et al.
Publicado: (2018)

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
por: Ordovás, Laura, et al.
Publicado: (2015)

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
por: Ordovás, Laura, et al.
Publicado: (2018)

Recombinase mediated cassette exchange into genomic targets using an adenovirus vector
por: Sorrell, David A., et al.
Publicado: (2010)

Hemichorea after hypoglycemic episodes with negative MRI findings in an elderly woman with poorly controlled type 2 diabetes mellitus: a case report
por: Matsushima, Eriko, et al.
Publicado: (2019)

A recombinase system facilitates cloning of expression cassettes in the ciliate Tetrahymena thermophila
por: Weide, Thomas, et al.
Publicado: (2007)

Enrichments of gene replacement events by Agrobacterium-mediated recombinase-mediated cassette exchange
por: Ebinuma, Hiroyasu, et al.
Publicado: (2015)

A Single Episode of Hypoglycemia as a Possible Early Warning Sign of Adrenal Insufficiency
por: Tanaka, Sho, et al.
Publicado: (2020)

Simplified Insertion of Transgenes Onto Balancer Chromosomes via Recombinase-Mediated Cassette Exchange
por: Sun, Florence F., et al.
Publicado: (2012)

Recombinase-mediated cassette exchange (RMCE) system for functional genomics studies in Mycoplasma mycoides
por: Noskov, Vladimir N, et al.
Publicado: (2015)

Recombinase-Mediated Cassette Exchange (RMCE)-in Reporter Cell Lines as an Alternative to the Flp-in System
por: Callesen, Morten M., et al.
Publicado: (2016)

Effects of GLP-1RA and SGLT2i, Alone or in Combination, on Mouse Models of Type 2 Diabetes Representing Different Disease Stages
por: Koike, Masao, et al.
Publicado: (2021)

Inverse Correlation Between Grip Strength and Serum Phosphorus: A Retrospective Observational Study in Japanese Elderly with Poorly Controlled Type 2 Diabetes
por: Tanaka, Sho, et al.
Publicado: (2020)

In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette
por: Sangiorgi, Eugenio, et al.
Publicado: (2008)

Recombinase-Mediated Cassette Exchange as a Novel Method To Study Somatic Hypermutation in Ramos Cells
por: Baughn, Linda B., et al.
Publicado: (2011)

Two Adult Siblings With Myotonic Dystrophy Type 1 With Different Phenotypes Presenting With Chronic Respiratory Insufficiency and Sleep Apnea Syndrome
por: Kohno, Genta, et al.
Publicado: (2019)

Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange
por: Wong, Ee Tsin, et al.
Publicado: (2005)

Floxed exon (Flexon): A flexibly positioned stop cassette for recombinase-mediated conditional gene expression
por: Shaffer, Justin M., et al.
Publicado: (2022)

Characterization of a complex context containing mecA but lacking genes encoding cassette chromosome recombinases in Staphylococcus haemolyticus
por: Zong, Zhiyong
Publicado: (2013)

Generation of minipigs with targeted transgene insertion by recombinase-mediated cassette exchange (RMCE) and somatic cell nuclear transfer (SCNT)
por: Jakobsen, Jannik Ejnar, et al.
Publicado: (2012)

Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti
por: Häcker, Irina, et al.
Publicado: (2017)

Targeted integration in CHO cells using CRIS-PITCh/Bxb1 recombinase–mediated cassette exchange hybrid system
por: Ghanbari, Samaneh, et al.
Publicado: (2022)

Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome
por: Han, Xiaosong, et al.
Publicado: (2019)

Identification of the CKM Gene as a Potential Muscle-Specific Safe Harbor Locus in Pig Genome
por: Xiong, Youcai, et al.
Publicado: (2022)

No safe harbor.
por: Holton, W C
Publicado: (1998)

Polymorphism of gene cassette promoter variants of class 1 integron harbored in S. Choleraesuis and Typhimurium isolated from Taiwan
por: Tseng, Chih-Sian, et al.
Publicado: (2014)

Rapid Emergence and Evolution of Staphylococcus aureus Clones Harboring fusC-Containing Staphylococcal Cassette Chromosome Elements
por: Baines, Sarah L., et al.
Publicado: (2016)

A Functional Comparison of the 3xP3 Promoter by Recombinase-Mediated Cassette Exchange in Drosophila and a Tephritid Fly, Anastrepha suspensa
por: Schetelig, Marc F., et al.
Publicado: (2013)

A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus
por: Lansing, Felix, et al.
Publicado: (2020)

Severe Hypertriglyceridemia Possibly Masked Acute Pancreatitis and Led to a Difficult Diagnosis in an Obese Patient with Ketoacidosis-onset Type 2 Diabetes
por: Fujishiro, Midori, et al.
Publicado: (2017)

Methicillin-Resistant Staphylococcus aureus Blood Isolates Harboring a Novel Pseudo-staphylococcal Cassette Chromosome mec Element
por: Yoon, Eun-Jeong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n51vq2uvo6g2u0m870nqudoj58