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Using recombinase‐mediated cassette exchange to engineer MIN6 insulin‐secreting cells based on a newly identified safe harbor locus
AIMS/INTRODUCTION: Recent studies have identified genomic and transcript level changes along with alterations in insulin secretion in patients with diabetes and in rodent models of diabetes. It is important to establish an efficient system for testing functional consequences of these changes. We aim...
Autores principales: | Furukawa, Asami, Tanaka, Aya, Yamaguchi, Suguru, Kosuda, Minami, Yamana, Midori, Nagasawa, Akiko, Kohno, Genta, Ishihara, Hisamitsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668067/ https://www.ncbi.nlm.nih.gov/pubmed/34382357 http://dx.doi.org/10.1111/jdi.13646 |
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