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The influence of 4-thiouridine labeling on pre-mRNA splicing outcomes

Metabolic labeling is a widely used tool to investigate different aspects of pre-mRNA splicing and RNA turnover. The labeling technology takes advantage of native cellular machineries where a nucleotide analog is readily taken up and incorporated into nascent RNA. One such analog is 4-thiouridine (4...

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Detalles Bibliográficos
Autores principales: Altieri, Jessie A. C., Hertel, Klemens J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668116/
https://www.ncbi.nlm.nih.gov/pubmed/34898625
http://dx.doi.org/10.1371/journal.pone.0257503