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VgrG-dependent effectors and chaperones modulate the assembly of the type VI secretion system

The type VI secretion system (T6SS) is a spear-like nanomachine found in gram-negative pathogens for delivery of toxic effectors to neighboring bacterial and host cells. Its assembly requires a tip spike complex consisting of a VgrG-trimer, a PAAR protein, and the interacting effectors. However, how...

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Detalles Bibliográficos
Autores principales: Liang, Xiaoye, Pei, Tong-Tong, Li, Hao, Zheng, Hao-Yu, Luo, Han, Cui, Yang, Tang, Ming-Xuan, Zhao, Ya-Jie, Xu, Ping, Dong, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668125/
https://www.ncbi.nlm.nih.gov/pubmed/34852023
http://dx.doi.org/10.1371/journal.ppat.1010116