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Limitations of lymphoblastoid cell lines for establishing genetic reference datasets in the immunoglobulin loci
Lymphoblastoid cell lines (LCLs) have been critical to establishing genetic resources for biomedical science. They have been used extensively to study human genetic diversity, genome function, and inform the development of tools and methodologies for augmenting disease genetics research. While the v...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668129/ https://www.ncbi.nlm.nih.gov/pubmed/34898642 http://dx.doi.org/10.1371/journal.pone.0261374 |