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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

β-hydroxybutyrate (β-OHB) is an essential metabolic energy source during fasting and functions as a chromatin regulator by lysine β-hydroxybutyrylation (Kbhb) modification of the core histones H3 and H4. We report that Kbhb on histone H3 (H3K9bhb) is enriched at proximal promoters of critical gene s...

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Detalles Bibliográficos
Autores principales: Terranova, Christopher J., Stemler, Kristina M., Barrodia, Praveen, Jeter-Jones, Sabrina L., Ge, Zhongqi, de la Cruz Bonilla, Marimar, Raman, Ayush, Cheng, Chia-Wei, Allton, Kendra L., Arslan, Emre, Yilmaz, Ömer H., Barton, Michelle C., Rai, Kunal, Piwnica-Worms, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668154/
https://www.ncbi.nlm.nih.gov/pubmed/34818540
http://dx.doi.org/10.1016/j.celrep.2021.110044