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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine
β-hydroxybutyrate (β-OHB) is an essential metabolic energy source during fasting and functions as a chromatin regulator by lysine β-hydroxybutyrylation (Kbhb) modification of the core histones H3 and H4. We report that Kbhb on histone H3 (H3K9bhb) is enriched at proximal promoters of critical gene s...
Autores principales: | Terranova, Christopher J., Stemler, Kristina M., Barrodia, Praveen, Jeter-Jones, Sabrina L., Ge, Zhongqi, de la Cruz Bonilla, Marimar, Raman, Ayush, Cheng, Chia-Wei, Allton, Kendra L., Arslan, Emre, Yilmaz, Ömer H., Barton, Michelle C., Rai, Kunal, Piwnica-Worms, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668154/ https://www.ncbi.nlm.nih.gov/pubmed/34818540 http://dx.doi.org/10.1016/j.celrep.2021.110044 |
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