In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes

The interactions of four sulfonylated Phe(3-Am)-derived inhibitors (MI-432, MI-463, MI-482 and MI-1900) of type II transmembrane serine proteases (TTSP) such as transmembrane protease serine 2 (TMPRSS2) were examined with serum albumin and cytochrome P450 (CYP) isoenzymes. Complex formation with alb...

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Detalles Bibliográficos
Autores principales: Pászti-Gere, Erzsébet, Szentkirályi, Anna, Fedor, Zsófia, Nagy, Gábor, Szimrók, Zoltán, Pászti, Zoltán, Pászti, Anna, Pilgram, Oliver, Steinmetzer, Torsten, Bodnárová, Slávka, Fliszár-Nyúl, Eszter, Poór, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668183/
https://www.ncbi.nlm.nih.gov/pubmed/34915414
http://dx.doi.org/10.1016/j.biopha.2021.112513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668183/
https://www.ncbi.nlm.nih.gov/pubmed/34915414
http://dx.doi.org/10.1016/j.biopha.2021.112513

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