3D-QSAR Studies of 1,2,4-Oxadiazole Derivatives as Sortase A Inhibitors

Sortase A (SrtA) is an enzyme that catalyzes the attachment of proteins to the cell wall of Gram-positive bacterial membrane, preventing the spread of pathogenic bacterial strains. Here, one class of oxadiazole compounds was distinguished as an efficient inhibitor of SrtA via the “S. aureus Sortase...

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Detalles Bibliográficos
Autores principales: Shakour, Neda, Hadizadeh, Farzin, Kesharwani, Prashant, Sahebkar, Amirhossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668286/
https://www.ncbi.nlm.nih.gov/pubmed/34912894
http://dx.doi.org/10.1155/2021/6380336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668286/
https://www.ncbi.nlm.nih.gov/pubmed/34912894
http://dx.doi.org/10.1155/2021/6380336

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