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Immunosuppressive mesenchymal stem cells aggregates incorporating hydrogel microspheres promote an in vitro invasion of cancer cells

INTRODUCTION: The objective of this study is to design a co-culture system of cancer cells and three-dimensional (3D) mesenchymal stem cells (MSC) aggregates for the in vitro evaluation of cancer invasion. METHODS: First, the MSC of an immunosuppressive phenotype (MSC2) were prepared by the MSC stim...

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Detalles Bibliográficos
Autores principales: Nii, Teruki, Tabata, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668441/
https://www.ncbi.nlm.nih.gov/pubmed/34977285
http://dx.doi.org/10.1016/j.reth.2021.11.006