Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease

Compromised autophagy and defective lysosomal clearance significantly contribute to impaired neuronal proteostasis, which represents a hallmark of Alzheimer's disease (AD) and other age-related neurodegenerative disorders. Growing evidence has implicated that modulating autophagic flux, instead...

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Detalles Bibliográficos
Autores principales: Xu, Shuting, Yang, Peng, Qian, Kang, Li, Yixian, Guo, Qian, Wang, Pengzhen, Meng, Ran, Wu, Jing, Cao, Jinxu, Cheng, Yunlong, Xu, Minjun, Zhang, Qizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668445/
https://www.ncbi.nlm.nih.gov/pubmed/34977433
http://dx.doi.org/10.1016/j.bioactmat.2021.09.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668445/
https://www.ncbi.nlm.nih.gov/pubmed/34977433
http://dx.doi.org/10.1016/j.bioactmat.2021.09.017

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